Manchester Metropolitan University

Introduction to Healthcare Science

Developing life-changing therapies and treatments for a diverse range of conditions and diseases.

World class healthcare research at Manchester Metropolitan University encompasses ground-breaking ideas with the potential to impact on society and improve quality of life. We work closely with colleagues from a wide range of disciplines to open up exciting new avenues of research.

In our state-of-the art labs we apply creative strategies in the fields of science and medicine from molecular to whole body systems. Our students benefit from cutting-edge advances made here, at the University, and beyond, though our global networks and partnerships with industry.

We develop potentially life-changing therapies, involving patients in our research to create individualised treatments in diverse areas; including dementia, muscular-skeletal rehabilitation, vascular pathology and microbiology. Manchester Metropolitan University Healthcare Science Research Centre: global solutions without limits.

Centre Contacts

Our expertise

Research Group

Neuroscience

Neuroscience is the study of the nervous system, both in health and disease, from molecules to human studies. The Neuroscience Group brings together like-minded researchers across several disciplines and faculties with expertise ranging from psychology, behaviour, neuropathology, neurophysiology, molecular and cellular neurobiology and computer science.

Major research lines are: Dementia, neuronal ageing, stroke, neuroinflammation, neurodevelopment, depression, mental health, stress, auditory and sensorimotor function and development, mathematical modelling of neurons, neuroendocrinology, neurophysiology, neuropathology, psychiatric genetics & epigenetics, psychology and neuropsychology

Research Group

Microbiology and Infection

The Microbiology and infection group is highly multidisciplinary and has a number of research and applied projects. We have a number of strong industrial and academic local, national and international collaborations.

There are four main areas:

  • Antimicrobial and hygienic coatings and surfaces (Food, Medical, Environmental) metals, polymers, encapsulated release, photocatalytic
  • Oral microbiology, dentures and cross infection and control
  • Antimicrobial and surface testing against planktonic bacteria and biofilms
  • Bacterial pathogen population structures, genomics / bioinformatics, phage therapy, synthetic biology (Staphylococcus aureus (incl. MRSA), Pseudomonas aeruginosa, Streptococcus pneumoniae, Klebsiella pneumoniae)

Area of expertise

Stem Cell Research

Stem cell research at Manchester Met is diverse but organised into focused areas spanning basic biology toward clinical investigation and therapeutic translation. We are utilising pluripotent stem cells to study neuronopathic disease, ageing and dementia. Expertise in hematopoietic stem cell (HSC) biology is being applied to better understand the development of HSC-related malignancies and HSC engraftment.

Manchester Met also has a critical mass of researchers investigating adult stem cell responses to muscular and vascular repair after injury. Finally, stem cell researchers are actively collaborating with chemists and engineers in the multi-disciplinary environment at Manchester Met to develop tissue-engineered grafts for orthopedic and cardiovascular disease.

Research Group

Neuromuscular and Skeletal Ageing

Group Lead

We combine advanced techniques in human clinical and exercise physiology with detailed molecular studies and stem-cell science to determine structure and function of muscles, their innervating nerves, surrounding capillaries and infiltrating immune cells. We aim to:

  • Understand and combat neuromuscular and skeletal declines that lead to common conditions such as weakness, sarcopenia, osteoporosis and frailty.
  • Optimise exercise performance and rehabilitation after disuse or injury in elite athletes and the general public at all ages.

We maintain international collaborations and are funded by the UK Medical Research Council; European Union; British Heart Founcdation and Nutricia Research (Danone).

Research Group

Cognitive Motor Function

The group, combines expertise in sensorimotor control, neurophysiology, postural control, balance and gait analysis, artificial intelligence, medical imaging analysis, high-performance computing, and engineering  control (e.g. intermittent control).

Areas of application include:

  • Innovative Muscle Analysis technology using ultrasound, artificial intelligence and computer vision. 
  • Neuromusculo-skeletal integration of muscle activation and tissue dynamics.
  • Gait, Ageing, Diabetes and Arthritis research, with a mainly clinical, biomechanics theme.
  • Sensorimotor control of balance, manual control and fear of falling (High Walkway).
  • Neurological conditions and movement disorders (Parkinsons, Dystonia, Motor Neurone Disease, Cerebral Palsy).

Research Group

Cardiovascular

Our interdisciplinary research with clinical and translational hypothesis-driven themes, aims to identify novel biomarkers of disease, thereby contributing to patient stratification and application of personalised medicine.

Our work is informed by productive collaborations with clinical cardiovascular-related teams along the Manchester academic corridor and within the Greater Manchester six Foundation Trusts, enabling Manchester Met to contribute on a competitive International stage of academic excellence.

There are six group leaders with 18 research, technical and managerial staff in total covering a research programme which includes; Endothelial dysfunction and repair, inflammation; biomarkers of disease; small molecule drug development; Vascular calcification; Endothelial progenitor cell function; acute coronary syndromes; thrombosis and haemostasis, vascular contractility, and nanomedicine.

Research Group

Pharmaceutical Chemistry

The Pharmaceutical Chemistry Group work on a number of chemistry themes which support research in Healthcare Science.

Our work on the construction of small molecule bioactives aids the development of new therapeutics and validates novel drug targets identified by the centre.

The groups work on microfluidic technology, electrochemical sensors and chemically enhanced imaging leads towards the development of point of care devices and forensic applications.

Research Group

Genetics Cell and Molecular Biology

The Genetics, Cells and Molecular Biology research group (GCMB) comprises a multi-disciplinary team of principle investigators (PIs) whose research cover many areas including diabetes and wound healing, aging, reproductive science, epigenetics, blood and cancer biology and stem cell biology. Many of these research themes overlap, with cross collaborations between PIs.

We employ a wide variety of techniques to address the fundamental and important questions in cell and molecular biology relating to disease and health.

GCMB collaborate with other groups within the faculty of Science and Engineering and institutions external to Manchester Met. We offer a vibrant research environment for postgraduate students and postdoctoral scientists.  

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