Introductory and medical microbiology; microbial genetics.
1. Genetic mechanisms of genomic instability and cell senescence under retarded telomere protection.
2.Impact of stress factors and drugs on telomere length.
3. Interactions between antimicrobials in treating infectious agents.
4. Cooperation between nuclear and organelle genomes during development.
PhD projects in subjects of yeast and plant genetics are available for individuals with self arranged funding.
EI. Zubko, JL. Shackleton, MK. Zubko (2016). ATLAS: an Advanced PCR-Method for Routine Visualization of Telomere Length in Saccharomyces cerevisiae. Int J Biol Macromol. pp.1-11.
MV. Sanchez-Puerta, MK. Zubko, JD. Palmer (2015). Homologous recombination and retention of a single form of most genes shape the highly chimeric mitochondrial genome of a cybrid plant. New Phytologist. 206(1), pp.381-396.
EI. Zubko, MK. Zubko (2014). Deficiencies in mitochondrial DNA compromise the survival of yeast cells at critically high temperatures. Microbiol Res. 169(2-3), pp.185-195.
EI. Zubko, MK. Zubko (2014). Deficiencies in mitochondrial DNA compromise the survival of yeast cells at critically high temperatures. Microbiological Research. 169(2-3), pp.185-195.
EI. Zubko, MK. Zubko (2013). Co-operative inhibitory effects of hydrogen peroxide and iodine against bacterial and yeast species. BMC Res Notes. 6,
SG. Addinall, M. Downey, M. Yu, MK. Zubko, J. Dewar, et al. (2008). A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae. Genetics. 180(4), pp.2251-2266.
I. Morin, H-P. Ngo, A. Greenall, MK. Zubko, N. Morrice, et al. (2008). Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response. EMBO J. 27(18), pp.2400-2410.
SS. Foster, MK. Zubko, S. Guillard, D. Lydall (2006). MRX protects telomeric DNA at uncapped telomeres of budding yeast cdc13-1 mutants. DNA Repair (Amst). 5(7), pp.840-851.
MK. Zubko, D. Lydall (2006). Linear chromosome maintenance in the absence of essential telomere-capping proteins. Nat Cell Biol. 8(7), pp.734-740.
M. Downey, R. Houlsworth, L. Maringele, A. Rollie, M. Brehme, et al. (2006). A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator. Cell. 124(6), pp.1155-1168.
MK. Zubko, L. Maringele, SS. Foster, D. Lydall (2006). Detecting repair intermediates in vivo: effects of DNA damage response genes on single-stranded DNA accumulation at uncapped telomeres in budding yeast. Methods Enzymol. 409, pp.285-300.
MK. Zubko, EI. Zubko, KV. Zuilen, P. Meyer, A. Day (2004). Stable transformation of petunia plastids. Transgenic Research. 13(6), pp.523-530.
MK. Zubko, S. Guillard, D. Lydall (2004). Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants. Genetics. 168(1), pp.103-115.
MK. Zubko (2004). Mitochondrial tuning fork in nuclear homeotic functions. Trends Plant Sci. 9(2), pp.61-64.
MK. Zubko, EI. Zubko, K. Adler, B. Grimm, YY. Gleba (2003). New CMS-associated phenotypes in cybrids Nicotiana tabacum L. (+Hyoscyamus niger L.). Ann Bot. 92(2), pp.281-288.
MK. Zubko, EI. Zubko, YY. Gleba (2002). Self-fertile cybrids Nicotiana tabacum (+Hyoscyamus aureus) with a nucleo-plastome incompatibility. Theoretical and Applied Genetics. 105(6-7), pp.822-828.
MK. Zubko, A. Day (2002). Differential regulation of genes transcribed by nucleus-encoded plastid RNA polymerase, and DNA amplification, within ribosome-deficient plastids in stable phenocopies of cereal albino mutants. Mol Genet Genomics. 267(1), pp.27-37.
MK. Zubko, EI. Zubko, AV. Ruban, K. Adler, HP. Mock, et al. (2001). Extensive developmental and metabolic alterations in cybrids Nicotiana tabacum (+ Hyoscyamus niger) are caused by complex nucleo-cytoplasmic incompatibility. Plant J. 25(6), pp.627-639.
K. Pyke, MK. Zubko, A. Day (2000). Marking cell layers with spectinomycin provides a new tool for monitoring cell fate during leaf development. J Exp Bot. 51(351), pp.1713-1720.
MK. Zubko, A. Day (1998). Stable albinism induced without mutagenesis: a model for ribosome-free plastid inheritance. Plant J. 15(2), pp.265-271.
MK. Zubko, EI. Zubko, YV. Patskovsky, OA. Khvedynich, J. Fisahn, et al. (1996). Novel 'homeotic' CMS patterns generated in Nicotiana via cybridization with Hyoscyamus and Scopolia. Journal of Experimental Botany. 47(301), pp.1101-1110.
AMG. Brown, KC. Lowe, MR. Davey, JB. Power, MK. Zubko (1995). Chemical mutagenesis and parthenolide biosynthesis in feverfew(tanacetum parthenium). Natural Product Letters. 7(4), pp.251-258.
MK. Zubko, K. Schmeer, WE. Gläßgen, E. Bayer, HU. Seitz (1993). Selection of anthocyanin-accumulating potato (Solanum tuberosum L.) cell lines from calli derived from seedlings produced by gamma-irradiated seeds. Plant Cell Reports. 12(10), pp.555-558.
A. Day, MK. Zubko, V. Kode, EA. Mudd, S. Iamtham (2003). Homologous recombination allows efficient isolation of marker-free transplastomic plants. In: PLANT BIOTECHNOLOGY 2002 AND BEYOND. ORLANDO, FL, 23/6/2002. pp.233-235.