I have extensive teaching experience in a number of disciplines within the biomedical sciences, at both undergraduate and postgraduate levels. My teaching specialisms include Human Physiology (including cardiovascular physiology), Immunology, Vascular Pharmacology and Nanomedicine. I use a wide range of delivery methods, including lectures, tutorials, and a number of alternative learning strategies to support a variety of learning styles, such as lecture-integrated and VLE supported case studies for large student groups (Azzawi & Dawson, 2007). My teaching and support of learning is underpinned by integration of pedagogic research. I am a fellow of the Higher Education Academy and am committed to teaching and learning to improve the student experience and satisfaction.
PhD 'Immunopathogenesis of Broncial Asthma', Imperial College, National Heart and Lung Institue, University of London, UK
MSc 'Applied Immunology', University of Brunel, UK
BSc (Hons) 'Physiology and Biochemistry' University of East London, UK
PGCert HE, University of Manchester, UK.
Postdoctoral Research Fellow, 2001-2005, Department of Medicine, University of Manchester
Postdoctoral Associate, 1991- 2000, University of Manchester.
Course Tutor for BSc Healthcare Science (Physiological Sciences) Degree Programme (stages 1 & 2).
Placement Co-ordinator for BSc Healthcare Science (Physiological Sciences) degree Programme.
Module Leader for a number of BSc and MSc units.
I have supervised over 20 postgraduate students (PhD, MRes, MSc) to succcessful completion. I am currently supervising 3 PhD students and 1 postdoctoral associate. Opportunities to study for a PhD, MRes, and MSc are open to students who have a passion for science, are enthusiastic and hardworking, with relevant background in Physiology, Pharmacy, or a Biomedical science discipline. Interdisciplinary projects within the area of Nanomedicine are also available.
External Examiner for PhD theses at various universities (including University College London; University of Manchester; University of Central Lancashire; University of Queensland [Australia]).
Research expertise in the following areas:
External Academic collaborations include:
Professor Clare Austin, Edgehill University
Dr Cathy Holt, University of Manchester
Professor Alexander Seifalian, University College London
Professor Mohsen Miraftab, University of Bolton
M. Azzawi (2017). Advances in biomaterial design and application for medical intervention. Nanomedicine. 12(18), pp.2151-2152.
M. Azzawi, T. Mohamed, S. Matou-Nasri, A. Farooq, D. Whitehead "PVP-coated gold nanoparticles inhibit endothelial cell viability, proliferation, ERK1/2 phosphorylation and reduce the magnitude of endothelial independent dilator responses in isolated aortic vessels",. International Journal of Nanomedicine.
M. Diaz, H. Degens, L. Vanhees, C. Austin, M. Azzawi (2016). The Effects of Resveratrol on Aging Vessels. Exp Gerontol. 85, pp.41-47.
A. Farooq, L. Tosheva, M. Azzawi, D. Whitehead (2016). Real-time observation of aortic vessel dilation through delivery of sodium nitroprusside via slow release mesoporous nanoparticles. J Colloid Interface Sci. 478, pp.127-135.
A. Shukur, D. Whitehead, A. Seifalian, M. Azzawi (2016). The influence of silica nanoparticles on small mesenteric arterial function. Nanomedicine. 11(16), pp.2131-2146.
M. Azzawi, A. Seifalian, W. Ahmed (2016). Nanotechnology for the diagnosis and treatment of diseases. Nanomedicine. 11(16), pp.2025-2027.
D. Karponis, M. Azzawi, A. Seifalian (2016). An arsenal of magnetic nanoparticles; Perspectives in the treatment of cancer. Nanomedicine. 11(16), pp.2215-2232.
A. Farooq, D. Whitehead, M. Azzawi (2014). Attenuation of endothelial-dependent vasodilator responses, induced by dye-encapsulated silica nanoparticles, in aortic vessels. Nanomedicine (Lond). 9(3), pp.413-425.
A. Farooq (2014). Restored Endothelial Dependent Vasodilation in Aortic Vessels after Uptake of Ceria Coated Silica Nanoparticles, ex vivo. Journal of Nanomedicine & Nanotechnology. 05(02),
A. Farooq, R. Al-Jowder, R. Narayanaswamy, M. Azzawi, PJR. Roche, et al. (2013). Gas detection using quenching fluorescence of dye-immobilised silica nanoparticles. Sensors and Actuators, B: Chemical. 183, pp.230-238.
A. Shukur, SB. Rizvi, D. Whitehead, A. Seifalian, M. Azzawi (2013). Altered sensitivity to nitric oxide donors, induced by intravascular infusion of quantum dots, in murine mesenteric arteries. Nanomedicine: Nanotechnology, Biology, and Medicine. 9(4), pp.532-539.
A. Shukur, SB. Rizvi, D. Whitehead, A. Seifalian, M. Azzawi (2013). Altered sensitivity to nitric oxide donors, induced by intravascular infusion of quantum dots, in murine mesenteric arteries. Nanomedicine. 9(4), pp.532-539.
N. Akbar, T. Mohamed, D. Whitehead, M. Azzawi (2011). Biocompatibility of amorphous silica nanoparticles: Size and charge effect on vascular function, in vitro. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY. 58(5), pp.353-362.
M. Azzawi, C. Austin (2007). The effects of endothelial factor inhibition on the time course of responses of isolated rat coronary arteries to intraluminal flow. JOURNAL OF VASCULAR RESEARCH. 44(3), pp.223-233.
M. Azzawi, C. Austin (2006). Extravascular pressure modulates responses of isolated rat coronary arteries to vasodilator, but not vasoconstrictor, stimuli. Am J Physiol Heart Circ Physiol. 290(3), pp.H1151-H1156.
M. Azzawi, SW. Kan, V. Hillier, N. Yonan, IV. Hutchinson, et al. (2005). The distribution of cardiac macrophages in myocardial ischaemia and cardiomyopathy. Histopathology. 46(3), pp.314-319.
M. Azzawi, C. Austin (2004). Myogenic regulation of isolated small coronary arteries following increases in extravascular pressure. Microvasc Res. 68(1), pp.71-74.
M. Azzawi, PS. Hasleton, DM. Turner, N. Yonan, AK. Deiraniya, et al. (2001). Tumor necrosis factor-alpha gene polymorphism and death due to acute cellular rejection in a subgroup of heart transplant recipients. Hum Immunol. 62(2), pp.140-142.
M. Azzawi, V. Pravica, PS. Hasleton, IV. Hutchinson (2001). A single nucleotide polymorphism at position --109 of the RANTES proximal promoter. Eur J Immunogenet. 28(1), pp.95-96.
M. Azzawi, P. Hasleton (1999). Tumour necrosis factor alpha and the cardiovascular system: its role in cardiac allograft rejection and heart disease. Cardiovasc Res. 43(4), pp.850-859.
M. Azzawi, PS. Hasleton, IV. Hutchinson (1999). TNF-α in acute cardiac transplant rejection. Cytokines, Cellular and Molecular Therapy. 5(1), pp.41-49.
M. Azzawi, PS. Hasleton, IV. Hutchinson (1999). TNF-alpha in acute cardiac transplant rejection. Cytokines Cell Mol Ther. 5(1), pp.41-49.
M. Azzawi, PS. Hasleton, PJ. Geraghty, N. Yonan, P. Krysiak, et al. (1998). RANTES chemokine expression is related to acute cardiac cellular rejection and infiltration by CD45RO T-lymphocytes and macrophages. J Heart Lung Transplant. 17(9), pp.881-887.
M. Azzawi, PS. Hasleton, SW. Kan, VF. Hillier, A. Quigley, et al. (1997). Distribution of myocardial macrophages in the normal human heart. J Anat. 191 ( Pt 3), pp.417-423.
M. Azzawi, SDC. Grant, PS. Hasleton, N. Yonan, CS. Campbell, et al. (1996). TNFα mRNA and protein in cardiac transplant biopsies: Comparison with serum TNFα levels. Cardiovascular Research. 32(3), pp.551-556.
M. Azzawi, SD. Grant, PS. Hasleton, N. Yonan, CS. Campbell, et al. (1996). TNF alpha mRNA and protein in cardiac transplant biopsies: comparison with serum TNF alpha levels. Cardiovasc Res. 32(3), pp.551-556.
M. Azzawi, PS. Hasleton, SC. Grant, JP. Stewart, IV. Hutchinson (1995). Interleukin-10 in human heart transplantation: an in situ hybridization study. The Manchester Transplant Cytokine Group. J Heart Lung Transplant. 14(3), pp.519-528.
M. AZZAWI, PS. HASLETON, SCD. GRANT, JP. STEWART, IV. HUTCHINSON (1995). INTERLEUKIN-10 IN HUMAN HEART-TRANSPLANTATION - AN IN-SITU HYBRIDIZATION STUDY. JOURNAL OF HEART AND LUNG TRANSPLANTATION. 14(3), pp.519-528.
M. AZZAWI, PW. JOHNSTON, S. MAJUMDAR, AB. KAY, PK. JEFFERY (1992). LYMPHOCYTES-T AND ACTIVATED EOSINOPHILS IN AIRWAY MUCOSA IN FATAL ASTHMA AND CYSTIC-FIBROSIS. AMERICAN REVIEW OF RESPIRATORY DISEASE. 145(6), pp.1477-1482.
A. Geada, S. Gaunt, M. Azzawi, S. Shimeld, J. Pearce, et al. (1992). Sequence and embryonic expression of the murine Hox-3.5 gene. Development.. 116, pp.497-506.
M. Azzawi, PW. Johnson, S. Majumdar, AB. Kay, PK. Jeffery (1992). T lymphocytes and activated eosinophils in airway mucosa in fatal asthma and cystic fibrosis. American review of respiratory diseases. 145(6), pp.1477-1482.
B. Bradley, M. Azzawi, MR. Jackobson, B. Assoufi, J. Collins, et al. (1991). Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness. Journal of Allergy and Clinical Immunology. 88(4), pp.661-674.
Q. Hamid, M. Azzawi, S. Ying, R. Moqbel, AJ. Wardlaw, et al. (1991). Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. Journal of Clinical Investigation. 87(5), pp.1541-1546.
Q. Hamid, M. Azzawi, S. Ying, R. Moqbel, AJ. Wardlaw, et al. (1991). Interleukin-5 mRNA in mucosal bronchial biopsies from asthmatic subjects. Int Arch Allergy Appl Immunol. 94(1-4), pp.169-170.
M. AZZAWI, B. BRADLEY, PK. JEFFERY, AJ. FREW, AJ. WARDLAW, et al. (1990). IDENTIFICATION OF ACTIVATED LYMPHOCYTES-T AND EOSINOPHILS IN BRONCHIAL BIOPSIES IN STABLE ATOPIC ASTHMA. AMERICAN REVIEW OF RESPIRATORY DISEASE. 142(6), pp.1407-1413.
AJ. Frew, R. Moqbel, M. Azzawi, A. Hartnell, J. Barkans, et al. (1990). T lymphocytes and eosinophils in allergen-induced late-phase asthmatic reactions in the guinea pig. Am Rev Respir Dis. 141(2), pp.407-413.
AJ. FREW, R. MOQBEL, M. AZZAWI, A. HARTNELL, J. BARKANS, et al. (1990). LYMPHOCYTES-T AND EOSINOPHILS IN ALLERGEN-INDUCED LATE-PHASE ASTHMATIC REACTIONS IN THE GUINEA-PIG. AMERICAN REVIEW OF RESPIRATORY DISEASE. 141(2), pp.407-413.
M. Azzawi, B. Bradley, PK. Jeffery, AJ. Frew, B. Assoufi, et al. (1990). Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma. American Review of respiratory diseases. 142, pp.1407-1413.
ME. Azzawi (2014). Assessment of Vascular Function and Contractility, Ex Vivo. M. Slevin, G. McDowell. In: Handbook of Vascular Biology Techniques. Springer Science+Business Media Dordrecht 2014, pp.65-79.
M. Azzawi (2012). The nanotoxicological influence of nanoparticles; with special reference to the vasculature. In: Current advances in the medical application of nanotechnology. Bentham Science publishers,
J. Feng, T. Rajeswaran, S. He, FL. Wilkinson, F. Serracino-Inglott, et al. (2015). Investigation of the composition of arterial plaques based on arterial waveforms and material properties. In: Conf Proc IEEE Eng Med Biol Soc. United States, 25/8/2015. pp.993-996.
M. Diaz, H. Degens, C. Austin, M. Azzawi (2015). 207 The Vascular Effects of Resveratrol on Aged Mouse Femoral Arteries. In: Heart. Manchester, ENGLAND, 8/6/2015. pp.A114.1-A114.
A. Shukur, D. Whitehead, AM. Seifalian, Y. Alexander, F. Wilkinson, et al. (2015). 173 Infused silica nanoparticles compromise vascular function in small mesenteric arteries. In: Heart. Manchester, ENGLAND, 8/6/2015. pp.A98.2-A98.
M. Azzawi, A. Qadeer, A. Aqel, N. Ahmed (2010). Age-induced impairment of dilator responses in small mesenteric arteries. In: 9TH WORLD CONGRESS FOR MICROCIRCULATION. Paris, FRANCE, 25/9/2010. pp.1-4.
T. Mohamed, D. Whitehead, M. Azzawi (2010). Attenuation of vasodilator responses, induced by nanoparticle uptake, in rat aortic rings. In: Proceedings of the Physiological Society.
M. Qadeer, M. Azzawi, N. Ahmed (2009). Influence of advanced glycation endproducts on vascular function of murine aortic vessels. Manchester, UK, 24/6/2009.
E. Benomran, N. Ahmed, M. Azzawi (2008). Attenuation of murine aortic vessel responses in the presence of proteins modified by advanced glycation end-products. In: Journal of vascular research.
E. Benomran, D. Maskew, N. Ahmed, M. Azzawi (2007). The influence of advanced glycation endproducts on aortic blood vessel function. Tripoli, Libya, 7/12/2007. pp.61-61.
M. Azzawi, C. Austin (2004). Autoregulation of Flow-induced dilator responses, in small rat coronary arteries, in vitro. In: Heart.
M. Azzawi, C. Austin (2003). Myogenic regulation during sustained elevations in extravascular pressure in the normal coronary artery from the rat. In: Journal of Physiology.
M. Azzawi, C. Austin (2003). Active regulation of coronary artery diameter in response to extravascular pressure elevation. In: Proc 3rd Federation of European Physiol Societies.
M. Azzawi, C. Austin (2002). The effects of intra- and extravascular pressure on rat coronary artery diameter. In: JOURNAL OF PHYSIOLOGY-LONDON. UNIV LIVERPOOL, LIVERPOOL, ENGLAND, 8/7/2002. pp.73P-73P.
M. Azzawi, C. Austin (2002). The influence of the endothelium on the modulation of rat coronary artery diameter after elevation of extravascular pressure. In: Journal of Physiology.
M. Azzawi (1996). The tissue distribution of macrophages within human hearts. In: European Journal of Haematology.
M. Azzawi (1996). RANTES chemokine expression in cardiac cellular rejection. European J Haematology 1996; 57 (59): p34. In: European J Haematology.
M. Azzawi (1995). Tumour necrosis factor alpha in human cardiac transplantation. In: Immunology.
ME. Azzawi (1990). Activated eosinophils and T lymphocytes in the bronchial mucosa in bronchial asthma. J All CLin Imm 1990; 85:p166. In: Journal of Allergy and Clinical Immunology.
M. Azzawi (1990). Activated eosinophils and T lymphocytes in the bronchial mucosa in bronchial asthma. In: Journal of Allergy and Clinical Immunology.
M. Azzawi (1989). Activated eosinophils in bronchi obtained at post-mortem from asthma deaths. In: Clin Exp Allergy.
M. Azzawi (1989). Activated T lymphocytes and eosinophils in bronchial biopsy specimens in asthma: association with airway hyperresponsiveness. In: Thorax.
Scientific organising committee member and co-chair of the International conference on Nanotechnology in Medicine, November 2015, Manchester, UK
Scientific organising committee member and co-chair of the International conference on Nanotechnology in Medicine, 7-9 November 2016, Warsaw, Poland.
Organising committee member of the forthcoming TCES annual meeting, July 2017, Manchester, UK.
Scientific organising committee member of the forthcoming European Nanomedicine Meeting, April 2017, London, UK
Specialist invited reviewer for a number of Journals including 'Nanomedicine-NBM'; 'Nanomedicine-Future medicine'; 'Biomaterials'; ‘Free Radical Biology and Medicine’; ‘Cardiovascular Research’; ‘Biomedical Research International’; 'International Journal of Nanomedicine', and ‘BioSystems'.
Reviewer of research grants for a number of funding bodies (including The Wellcome trust; BBSRC)
1. Innovate UK (Technology Strategy Board), October 2014. Development of a co-culture cardiovascular model for toxicity testing. £249,481. MMU principal investigator, with lead industrial partner Kirkstall Ltd, and collaborating partner Elisha systems.
2. Faculty PhD studentship (MMU), January 2016 (3 years). Use of Ceria
Nanoparticles to restore vascular dysfunction in aging. Principal applicant.
3. Greater Manchester Academic Health Science Network [GM AHSN], August 2014. A novel haemodynamic device to detect vulnerable plaques based on arterial waveforms, £40,000. Co-investigator.
4. Faculty PhD studentship (MMU), January 2014 (3 years). The effectiveness of
lower-limb Vascular Occlusion Training [VOT] post lower limb injury. Co-Investigator.
5. Erasmus Mundus PhD studentship programme, September 2013 (3 years), €108,000. “Impaired mobility in aging; the role of antioxidants in improving vascular function”. Principal investigator.
6. Erasmus Mundus PhD studentship programme, September 2013 (3 years), €108,000. “Effects of home-based training in patients with ischaemic artery disease”. Co-Investigator.
7. Support of excellence award, Healthcare Science Research Centre, MMU, March 2016. £7,205.
7. Research incentivisation Award (MMU), November 2014. The generation, optimisation and testing of artificial blood vessel scaffolds that mimic vascular physiological responses. £5,000. Co-I
8. Research incentivisation Award (MMU), January 2014 (1 year). Development of a novel tissue engineered vascular graft for toxicology testing. £5,000. Co-I
9. NanoInfoBio, Early adopter fund (EPSRC), October 2010 (1 year), £10,000. “Investigation into the mechanism of altered vascular function, induced by nanoparticles”. Principal investigator.
Public Engagement in Science (Manchester Science Festival- The 'heart Model'). Outreach activities.
Kirkstall Ltd, Rotherham, UK
Elisha Systems Ltd., Leeds, UK
Fellow of the Higher Education Academy.
Expert reviewer for a number of grant funding bodies (including the Wellcome Trust).
Lead guest editor for the special issue of the journal 'Nanomedicine', August 2016.
Committee member of the British society for cardiovascular research (elected 2016); Executive member of the British Society for Nanomedicine; Member of the Physiological Society; Member of the British microcirculation Society; Member of the Northern Vascular Biology Research group.