Beatriz Maciá graduated in Chemistry at the University of Alicante (Spain), and obtained her PhD in 2005 working in ‘Arene Catalyzed Lithiation Processes’ with Professor Miguel Yus at the same University. In 2006 she joined the group of Professor Ben L. Feringa in Groningen, The Netherlands, as a postdoctoral fellow, where she worked in asymmetric catalysis and molecular nanotechnology. From February 2010 to May 2012, she held an Assistant Professor position in the Department of Organic Chemistry at the University of Alicante where she started her independent research, focused on organic synthesis and asymmetric catalysis. In June 2012, Beatriz Maciá joined the School of Natural Sciences at Manchester Metropolitan University as a Lecturer in Organic Chemistry.
I teach Organic Chemistry in the following units:
Inorganic and Organic Chemistry - Year 1
Advanced Chemistry Concepts 1 - Year 3
Sep 2005 - PhD Award - University of Alicante, Spain.
Title: ´DTBB-Catalysed lithiation: double lithiation, reductive ring opening of oxiranes and [2,3]-Wittig rearrangement´
Supervisors: Miguel Yus and Cecilia Gomez
June 2003 - Master Thesis - University of Alicante, Spain.
Title: ´Functionalization of 1,3-dichloro-2-butene through organolithium intermediates´
Supervisor: Cecilia Gomez
June 2001 - Bachelor in Chemistry - University of Alicante, Spain
March 2010 - June 2012: Assistant professor in Organic Chemistry. Faculty of Sciences, University of Alicante. Spain.
March 2006 - February 2010: Postdoctoral Researcher. Stratingh Institute for Chemistry and Chemical Engineering. University of Groningen. The Netherlands.
Erasmus coordinator - Department of Natural Sciences
Asymmetric Catalysis
Organometallic Chemistry
Transition Metal Catalyzed C-C Bond Formation
JF. Collados, R. Solaì, SR. Harutyunyan, B. Maciá (2016). Catalytic Synthesis of Enantiopure Chiral Alcohols via Addition of Grignard Reagents to Carbonyl Compounds. ACS Catalysis. 6(3), pp.1952-1970.
F. Taday, J. Ryan, SP. Argent, V. Caprio, B. Maciá, et al. E. O'Reilly. (2020). Asymmetric Construction of Alkaloids Employing a Key ω-Transaminase Cascade. Chemistry - A European Journal. 26(17), pp.3729-3732.
K. Naksomboon, Y. Álvarez-Casao, M. Uiterweerd, N. Westerveld, B. Maciá, et al. MÁ. Fernández-Ibáñez. (2018). S,O-ligand-promoted palladium-catalyzed C-H olefination of arenes with allylic substrates. Tetrahedron Letters. 59(4), pp.379-382.
R. Solà, OB. Sutcliffe, CE. Banks, B. Maciá (2017). Ball mill and microwave assisted synthetic routes to Fluoxetine. Sustainable Chemistry and Pharmacy. 5, pp.14-21.
K. Naksomboon, C. Valderas, B. Maciá, M. Fernández-Ibáñez (2017). Synthesis of α-Substituted Diphenylphosphinocarboxylic Acids and Their Palladium Complexes. Synlett. 28(2), pp.221-224.
M. Veguillas, R. Solà, M. Fernández-Ibañez, B. Maciá (2016). Catalytic enantioselective addition of methyltriisopropoxititanium to aldehydes. Tetrahedron Asymmetry. 27(14-15), pp.643-648.
JF. Collados, R. Solaì, SR. Harutyunyan, B. Maciá (2016). Catalytic Synthesis of Enantiopure Chiral Alcohols via Addition of Grignard Reagents to Carbonyl Compounds. ACS Catalysis. 6(3), pp.1952-1970.
M. Veguillas, R. Solà, L. Shaw, B. Maciá (2016). Catalytic Asymmetric Addition of Organolithium Reagents to Aldehydes. European Journal of Organic Chemistry. 2016(9), pp.1788-1794.
E. Fernández-Mateos, B. Maciá, M. Yus (2014). Catalytic enantioselective addition of aryl grignard reagents to ketones. European Journal of Organic Chemistry. 2014(29), pp.6519-6526.
MA. Fernández-Ibañez, B. Maciá, DA. Alonso, IM. Pastor (2013). Palladium and organocatalysis: An excellent recipe for asymmetric synthesis. Molecules. 18(9), pp.10108-10121.
MA. Fernández-Ibáñez, B. Maciá, DA. Alonso, IM. Pastor (2013). Recent advances in the catalytic enantioselective Reformatsky reaction. European Journal of Organic Chemistry. pp.7028-7034.
E. Fernández-Mateos, B. Maciá, M. Yus (2013). Catalytic enantioselective addition of alkyl grignard reagents to aliphatic aldehydes. Advanced Synthesis and Catalysis. 355(7), pp.1249-1254.
MA. Fernández-Ibáñez, B. Maciá, DA. Alonso, IM. Pastor (2013). Recent Advances in the Catalytic Enantioselective Reformatsky Reaction. European Journal of Organic Chemistry.
E. Fernández-Mateos, B. Maciá, M. Yus (2013). Catalytic Enantioselective Addition of Alkyl Grignard Reagents to Aliphatic Aldehydes. Advanced Synthesis and Catalysis. 342(8),
E. Fernandez-Mateos, B. Macia, M. Yus (2012). Catalytic Asymmetric Addition of Alkyllithium Reagents to Aromatic Aldehydes. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2012(20), pp.3732-3736.
E. Fernandez-Mateos, B. Macia, M. Yus (2012). Catalytic enantioselective addition of organoaluminum reagents to aldehydes. TETRAHEDRON-ASYMMETRY. 23(10), pp.789-794.
E. Fernandez-Mateos, B. Macia, DJ. Ramon, M. Yus (2011). Catalytic Enantioselective Addition of MeMgBr and Other Grignard Reagents to Aldehydes. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2011(34), pp.6851-6855.
T. Kudernac, N. Ruangsupapichat, M. Parschau, B. Maciá, N. Katsonis, et al. SR. Harutyunyan, K-H. Ernst, BL. Feringa. (2011). Electrically driven directional motion of a four-wheeled molecule on a metal surface. Nature. 479(7372), pp.208-211.
AC. Coleman, JM. Beierle, MCA. Stuart, B. Maciá, G. Caroli, et al. JT. Mika, DJ. van Dijken, J. Chen, WR. Browne, BL. Feringa. (2011). Light-induced disassembly of self-assembled vesicle-capped nanotubes observed in real time. Nat Nanotechnol. 6(9), pp.547-552.
T. den Hartog, A. Rudolph, B. Maciá, AJ. Minnaard, BL. Feringa (2010). Copper-Catalyzed Enantioselective Synthesis of trans-1-Alkyl-2-substituted Cyclopropanes via Tandem Conjugate Addition−Intramolecular Enolate Trapping. Journal of the American Chemical Society. 132(41), pp.14349-14351.
MA. Fernández-Ibáñez, B. Maciá, A. Minnaard, B. Feringa (2010). Catalytic enantioselective reformatsky reaction with aldehydes. Chemtracts. 23(5), pp.215-218.
T. den Hartog, B. Macia, AJ. Minnaard, BL. Feringa (2010). Copper-Catalyzed Asymmetric Allylic Alkylation of Halocrotonates: Efficient Synthesis of Versatile Chiral Multifunctional Building Blocks. ADVANCED SYNTHESIS & CATALYSIS. 352(6), pp.999-1013.
PH. Bos, B. Maciá, MA. Fernández-Ibáñez, AJ. Minnaard, BL. Feringa (2010). Catalytic asymmetric conjugate addition of dialkylzinc reagents to alpha,beta-unsaturated sulfones. Org Biomol Chem. 8(1), pp.47-49.
MÁ. Fernández‐Ibáñez, B. Maciá, MG. Pizzuti, AJ. Minnaard, BL. Feringa (2009). Catalytic Enantioselective Addition of Dialkylzinc Reagents to N‐Acylpyridinium Salts. Angewandte Chemie International Edition. 48(49), pp.9339-9341.
MA. Fernández-Ibáñez, B. Maciá, AJ. Minnaard, BL. Feringa (2008). Catalytic enantioselective Reformatsky reaction with ortho-substituted diarylketones. Org Lett. 10(18), pp.4041-4044.
MA. Fernández-Ibáñez, B. Maciá, AJ. Minnaard, BL. Feringa (2008). Catalytic enantioselective Reformatsky reaction with ketones. Chem Commun (Camb). pp.2571-2573.
B. Macia, MA. Fernandez-Ibanez, N. Mrsic, AJ. Minnaard, BL. Feringa (2008). Copper-catalyzed enantioselective conjugate addition of Grignard reagents to acyclic enones using monodentate phosphoramidite ligands. TETRAHEDRON LETTERS. 49(11), pp.1877-1880.
MA. Fernández-Ibáñez, B. Maciá, AJ. Minnaard, BL. Feringa (2008). Catalytic enantioselective reformatsky reaction with aldehydes. Angew Chem Int Ed Engl. 47(7), pp.1317-1319.
BM. Ruiz, K. Geurts, MA. Fernandez-Ibanez, B. ter Horst, AJ. Minnaard, et al. BL. Feringa. (2007). Highly versatile enantioselective conjugate addition of Grignard reagents to alpha,beta-unsaturated thioesters. ORGANIC LETTERS. 9(24), pp.5123-5126.
C. Gomez, B. Macia, VJ. Lillo, M. Yus (2006). [1,2]-Wittig rearrangement from chloromethyl ethers. TETRAHEDRON. 62(42), pp.9832-9839.
C. Gomez, B. Macia, T. Soler, M. Yus (2005). Bis(chloromethyl) sulfone and sulfoxide as precursors of the corresponding alpha,alpha-dianionic synthons by a chlorine-lithium exchange. SYNTHESIS-STUTTGART. pp.3095-3102.
C. Gomez, B. Macia, M. Yus (2005). DTBB-catalysed lithiation of 1,2-bis(phenylsulfanyl)ethene: does 1-lithio-2-phenylsulfanylethene really exist?. TETRAHEDRON. 61(39), pp.9325-9330.
B. Macia, C. Gomez, M. Yus (2005). [2,3]-Wittig rearrangement by a chlorine-lithium exchange. TETRAHEDRON LETTERS. 46(36), pp.6101-6104.
M. Yus, B. Macia, C. Gomez, T. Soler, LR. Falvello, et al. PE. Fanwick. (2005). Reductive ring opening of cis- and trans-2,3-diphenyloxirane: a common intermediate. TETRAHEDRON. 61(15), pp.3865-3871.
C. Gomez, B. Macia, M. Yus (2005). DTBB-catalyzed lithiation of 2,6-bis(chloromethyl) pyridine. ARKIVOC. pp.10-20.
M. Yus, B. Macia, C. Gomez (2003). 1,3-dichloro-2-butene: a useful precursor for the 2-butene-1,3-dianion and its corresponding 1,3-dipolar synthon. TETRAHEDRON. 59(28), pp.5183-5192.
Research Opportunities: Applications or expressions of interest from undergraduate and postgraduate students are welcome. At the moment, postdoctoral researchers are strongly encouraged to apply for independent funding. Candidates will receive support and assistance with these applications. If interested, please contact Dr. Maciá (email: b.macia-ruiz@mmu.ac.uk) for further details.
Nov 2015: RS International Grant. Collaboration with University of Amsterdam.
May 2014: Royal Society of Chemistry – EPSRC 1st Grant Scheme.
May 2013: European Commission – Marie Curie Integration Career Scheme (FP7-PEOPLE-2012-CIG).
June 2013: Research Accelerator Grant (Manchester Metropolitan University).
June 2003: University of Alicante - Master degree award (San Alberto Magno Prize).
2001- 2005: Spanish Ministry of Education, Culture and Sport - PhD Fellowship.
June 2001: Ministry of Culture, Education and Sciences. Generalitat Valenciana - Extraordinary Award for Bachelor in Chemistry.
June 2001: University of Alicante - Best Graduate Student Award.
2000- 2001: Spanish Ministry of Education and Science - Undergraduate Scholarship.