Dr Mikhajlo Zubko
Senior Lecturer
My profile
Teaching
How I’ll teach you
Introductory and medical microbiology; microbial genetics.
Research outputs
1. Genetic mechanisms of genomic instability and cell senescence under retarded telomere protection.
2.Impact of stress factors and drugs on telomere length.
3. Interactions between antimicrobials in treating infectious agents.
4. Cooperation between nuclear and organelle genomes during development.
PhD projects in subjects of yeast and plant genetics are available for individuals with self arranged funding.
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Journal articles
Zubko, M.K. (2024) 'Towards sustainable antimicrobials from plants: some ways to abridge current methodological approaches.' Sustainable Materials and Technologies, 39
Platania, V., Douglas, T.E.L., Zubko, M.K., Ward, D., Pietryga, K., Chatzinikolaidou, M. (2021) 'Phloroglucinol-enhanced whey protein isolate hydrogels with antimicrobial activity for tissue engineering.' Materials Science and Engineering C, 129
Gandini, C.L., Ibañez, V.N., Zubko, M.K., Sanchez-Puerta, M.V. (2021) 'Complete plastome phylogeny and an update on cox1 intron evolution of Hyoscyameae (Solanaceae).' Organisms Diversity and Evolution, 21(3) pp. 521-532.
Jamieson, O., Betlem, K., Mansouri, N., Crapnell, R.D., Vieira, F.S., Hudson, A., Banks, C.E., Liauw, C.M., Gruber, J., Zubko, M., Whitehead, K.A., Peeters, M. (2021) 'Electropolymerised molecularly imprinted polymers for the heat-transfer based detection of microorganisms: A proof-of-concept study using yeast.' Thermal Science and Engineering Progress, 24
Betlem, K., Kaur, A., Hudson, A.D., Crapnell, R.D., Hurst, G., Singla, P., Zubko, M., Tedesco, S., Banks, C.E., Whitehead, K., Peeters, M. (2019) 'Heat-Transfer Method: A Thermal Analysis Technique for the Real-Time Monitoring of Staphylococcus aureus Growth in Buffered Solutions and Digestate Samples.' ACS Applied Bio Materials, 2(9) pp. 3790-3798.
Yeates, A.M., Zubko, M.K., Ruban, A.V. (2019) 'Absence of photosynthetic state transitions in alien chloroplasts.' Planta, 250(2) pp. 589-601.
Garcia, L.E., Zubko, M.K., Zubko, E.I., Sanchez-Puerta, M.V. (2019) 'Elucidating genomic patterns and recombination events in plant cybrid mitochondria.' Plant Molecular Biology, 100(4-5) pp. 433-450.
Betlem, K., Hoksbergen, S., Mansouri, N., Down, M., Losada-Perez, P., Eersels, K., van Grinsven, B., Cleij, T., Kelly, P., Sawtell, D., Zubko, M., Banks, C., Peeters, M. (2018) 'Real-time analysis of microbial growth by means of the Heat-Transfer Method (HTM) using Saccharomyces cerevisiae as model organism.' Physics in Medicine, 6pp. 1-8.
Zubko, E.I., Shackleton, J.L., Zubko, M.K. (2016) 'ATLAS: an Advanced PCR-Method for Routine Visualization of Telomere Length in Saccharomyces cerevisiae.' International Journal of Biological Macromolecules, 93(Part A) pp. 1285-1294.
Sanchez-Puerta, M.V., Zubko, M.K., Palmer, J.D. (2015) 'Homologous recombination and retention of a single form of most genes shape the highly chimeric mitochondrial genome of a cybrid plant..' New Phytol, 206(1) pp. 381-396.
Zubko, E.I., Zubko, M.K. (2014) 'Deficiencies in mitochondrial DNA compromise the survival of yeast cells at critically high temperatures.' Microbiological Research, 169(2-3) pp. 185-195.
Zubko, E.I., Zubko, M.K. (2013) 'Co-operative inhibitory effects of hydrogen peroxide and iodine against bacterial and yeast species..' BMC Res Notes, 6
Addinall, S.G., Downey, M., Yu, M., Zubko, M.K., Dewar, J., Leake, A., Hallinan, J., Shaw, O., James, K., Wilkinson, D.J., Wipat, A., Durocher, D., Lydall, D. (2008) 'A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae..' Genetics, 180(4) pp. 2251-2266.
Morin, I., Ngo, H.P., Greenall, A., Zubko, M.K., Morrice, N., Lydall, D. (2008) 'Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response..' EMBO J, 27(18) pp. 2400-2410.
Foster, S.S., Zubko, M.K., Guillard, S., Lydall, D. (2006) 'MRX protects telomeric DNA at uncapped telomeres of budding yeast cdc13-1 mutants..' DNA Repair (Amst), 5(7) pp. 840-851.
Zubko, M.K., Lydall, D. (2006) 'Linear chromosome maintenance in the absence of essential telomere-capping proteins..' Nat Cell Biol, 8(7) pp. 734-740.
Zubko, M.K., Maringele, L., Foster, S.S., Lydall, D. (2006) 'Detecting repair intermediates in vivo: effects of DNA damage response genes on single-stranded DNA accumulation at uncapped telomeres in budding yeast..' Methods Enzymol, 409pp. 285-300.
Downey, M., Houlsworth, R., Maringele, L., Rollie, A., Brehme, M., Galicia, S., Guillard, S., Partington, M., Zubko, M.K., Krogan, N.J., Emili, A., Greenblatt, J.F., Harrington, L., Lydall, D., Durocher, D. (2006) 'A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator..' Cell, 124(6) pp. 1155-1168.
Zubko, M.K., Zubko, E.I., Zuilen, K.V., Meyer, P., Day, A. (2004) 'Stable transformation of petunia plastids.' Transgenic Research, 13(6) pp. 523-530.
Zubko, M.K., Guillard, S., Lydall, D. (2004) 'Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants..' Genetics, 168(1) pp. 103-115.
Zubko, M.K. (2004) 'Mitochondrial tuning fork in nuclear homeotic functions..' Trends Plant Sci, 9(2) pp. 61-64.
Zubko, M.K., Zubko, E.I., Adler, K., Grimm, B., Gleba, Y.Y. (2003) 'New CMS-associated phenotypes in cybrids Nicotiana tabacum L. (+Hyoscyamus niger L.)..' Ann Bot, 92(2) pp. 281-288.
Zubko, M.K., Zubko, E.I., Gleba, Y.Y. (2002) 'Self-fertile cybrids Nicotiana tabacum (+Hyoscyamus aureus) with a nucleo-plastome incompatibility.' Theoretical and Applied Genetics, 105(6-7) pp. 822-828.
Zubko, M.K., Day, A. (2002) 'Differential regulation of genes transcribed by nucleus-encoded plastid RNA polymerase, and DNA amplification, within ribosome-deficient plastids in stable phenocopies of cereal albino mutants..' Mol Genet Genomics, 267(1) pp. 27-37.
Zubko, M.K., Zubko, E.I., Ruban, A.V., Adler, K., Mock, H.P., Misera, S., Gleba, Y.Y., Grimm, B. (2001) 'Extensive developmental and metabolic alterations in cybrids Nicotiana tabacum (+ Hyoscyamus niger) are caused by complex nucleo-cytoplasmic incompatibility..' Plant J, 25(6) pp. 627-639.
Pyke, K., Zubko, M.K., Day, A. (2000) 'Marking cell layers with spectinomycin provides a new tool for monitoring cell fate during leaf development..' J Exp Bot, 51(351) pp. 1713-1720.
Zubko, M.K., Day, A. (1998) 'Stable albinism induced without mutagenesis: a model for ribosome-free plastid inheritance..' Plant J, 15(2) pp. 265-271.
Zubko, M.K., Zubko, E.I., Patskovsky, Y.V., Khvedynich, O.A., Fisahn, J., Gleba, Y.Y., Schieder, O. (1996) 'Novel 'homeotic' CMS patterns generated in Nicotiana via cybridization with Hyoscyamus and Scopolia.' Journal of Experimental Botany, 47(301) pp. 1101-1110.
Brown, A.M.G., Lowe, K.C., Davey, M.R., Power, J.B., Zubko, M.K. (1995) 'Chemical mutagenesis and parthenolide biosynthesis in feverfew(tanacetum parthenium).' Natural Product Letters, 7(4) pp. 251-258.
Zubko, M.K., Schmeer, K., Gläßgen, W.E., Bayer, E., Seitz, H.U. (1993) 'Selection of anthocyanin-accumulating potato (Solanum tuberosum L.) cell lines from calli derived from seedlings produced by gamma-irradiated seeds.' Plant Cell Reports, 12(10) pp. 555-558.
Sidorov, V.A., Zubko, M.K., Kuchko, A.A., Komarnitsky, I.K., Gleba, Y.Y. (1987) 'Somatic hybridization in potato: use of γ-irradiated protoplasts of Solanum pinnatisectum in genetic reconstruction.' Theoretical and Applied Genetics, 74(3) pp. 364-368.
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Conference papers
Day, A., Zubko, M.K., Kode, V., Mudd, E.A., Iamtham, S. (2003) 'Homologous recombination allows efficient isolation of marker-free transplastomic plants.' In 10th IAPTC&B Congress. ORLANDO, FL, 23/6/2002 - 28/6/2002. Vasil, I.K. (ed.) SPRINGER, pp. 233-235.