FHEA PGCAP CBiol PhD BSc
Head of Division (Biomedical Sciences)
The BSc (Hons) Healthcare Science (Life Sciences) degree is a professional qualification required to legally register and practise in the healthcare arena (e.g. NHS or private sector) as a biomedical scientist or healthcare science practitioner. You can choose from 3 routes (Cellular Sciences, Blood Sciences or Infection Sciences). You will complete a work-based placement that prepares you with the clinical skills and expertise required for healthcare science practice; including the diagnosis, monitoring and management of human diseases. During the degree you will develop detailed understanding and knowledge of the biomedical areas of your chosen specialist route. The programme is accredited by Health Education England (HEE) and the Institute of Biomedical Science (IBMS). The degree is also approved by the Health and Care Professions Council (HCPC).
The BSc (Hons) Biomedical Science degree will develop your understanding of the human body in relation to health and disease. You will learn about cell biology, human physiology, medical microbiology, immunology, haematology & transfusion, genetics, biochemistry and pathology. The course is very practical-based and you will develop skills in analytic and diagnostic techniques applicable to biomedical science. The programme is accredited by the Institute of Biomedical Science (IBMS) and the Royal Society of Biology (RSB).
See the MMU website for full course details and entry requirements etc.
Dr Ashworth teaches on the undergraduate BSc (Hons) Biomedical Science and BSc (Hons) Healthcare Science (Life Sciences) degree programmes.
Dr Ashworth teaches on the taught MSc Biomedical Science and MBiomedSci Biomedical Science programmes.
Dr Ashworth supervises postgraduate research (MRes, MPhil, PhD) students.
External Examiner: Newcastle & Teeside University
Inflammation, Infection, Ageing & Tissue/Wound Repair
Dr Ashworth also collaborates on projects with other academics in the fields of medical microbiology, vascular science, human physiology, reproductive science, genetics, chemistry & food/nutrition science.
A. Fadel, J. Ashworth, A. Plunkett, Y. Mahmoud, Y. Ranneh, et al. (2018). Improving the extractability of arabinoxylans and the molecular weight of wheat endosperm using extrusion processing. Journal of Cereal Science. 84, pp.55-61.
NR. Sproston, M. El Mohtadi, M. Slevin, W. Gilmore, JJ. Ashworth (2018). The Effect of C-Reactive Protein Isoforms on Nitric Oxide Production by U937 Monocytes/Macrophages. Frontiers in Immunology. 9, pp.1-14.
A. Fadel, A. Plunkett, W. Li, V. Gyamfi, R. Nyaranga, et al. (2018). Modulation of Innate and Adaptive Immune Responses by Arabinoxylans. Journal of Food Biochemistry. 42(2: e12473),
A. Fadel, AM. Mahmoud, JJ. Ashworth, W. Li, YL. Ng, et al. (2018). Health-related effects and improving extractability of cereal arabinoxylans. International Journal of Biological Macromolecules. 109, pp.819-831.
A. Fadel, A. Plunkett, J. Ashworth, AM. Mahmoud, Y. Ranneh, et al. (2018). The effect of extrusion screw-speed on the water extractability and molecular weight distribution of arabinoxylans from defatted rice bran. Journal of Food Science and Technology. 55(3), pp.1201-1206.
Z. Zhang, C. Smith, JJ. Ashworth, W. Li (2018). Regulation of inducible nitric oxide synthase by arabinoxylans with molecular characterisation from wheat flour in cultured human monocytes. International Journal of Food Science and Technology. 53(5), pp.1294-1302.
A. Fadel, A. Plunkett, W. Li, Y. Ranneh, V. Gyamfi, et al. (2018). Arabinoxylans from rice bran and wheat immunomodulatory potentials: A Review Article. Nutrition & Food Science. 48(1), pp.97-110.
Z. Zhang, C. Smith, W. Li, J. Ashworth (2016). Characterization of Nitric Oxide Modulatory Activities of Alkaline-Extracted and Enzymatic-Modified Arabinoxylans from Corn Bran in Cultured Human Monocytes. Journal of Agricultural and Food Chemistry. 64(43), pp.8128-8137.
E. Boras, M. Slevin, MY. Alexander, A. Aljohi, W. Gilmore, et al. (2014). Monomeric C-reactive protein and Notch-3 co-operatively increase angiogenesis through PI3K signalling pathway. Cytokine. 69(2), pp.165-179.
AMW. Yau, AD. Moss, LJ. James, W. Gilmore, JJ. Ashworth, et al. (2014). The influence of angiotensin converting enzyme and bradykinin receptor B2 gene variants on voluntary fluid intake and fluid balance in healthy men during moderate-intensity exercise in the heat. Applied Physiology, Nutrition and Metabolism. 40(2), pp.184-190.
GS. Ashcroft, M-J. Jeong, JJ. Ashworth, M. Hardman, W. Jin, et al. (2012). Tumor necrosis factor-alpha (TNF-α) is a therapeutic target for impaired cutaneous wound healing. Wound Repair Regen. 20(1), pp.38-49.
JJ. Ashworth, JV. Smyth, N. Pendleton, M. Horan, A. Payton, et al. (2008). Polymorphisms spanning the 0N exon and promoter of the estrogen receptor-beta (ERbeta) gene ESR2 are associated with venous ulceration. Clin Genet. 73(1), pp.55-61.
S. O'Hagan, WB. Dunn, JD. Knowles, D. Broadhurst, R. Williams, et al. (2007). Closed-loop, multiobjective optimization of two-dimensional gas chromatography/mass spectrometry for serum metabolomics. Anal Chem. 79(2), pp.464-476.
SC. Gilliver, JJ. Ashworth, GS. Ashcroft (2007). The hormonal regulation of cutaneous wound healing. Clin Dermatol. 25(1), pp.56-62.
SC. Gilliver, JJ. Ashworth, SJ. Mills, MJ. Hardman, GS. Ashcroft (2006). Androgens modulate the inflammatory response during acute wound healing. J Cell Sci. 119(Pt 4), pp.722-732.
SJ. Mills, JJ. Ashworth, SC. Gilliver, MJ. Hardman, GS. Ashcroft (2005). The sex steroid precursor DHEA accelerates cutaneous wound healing via the estrogen receptors. J Invest Dermatol. 125(5), pp.1053-1062.
JJ. Ashworth, JV. Smyth, N. Pendleton, M. Horan, A. Payton, et al. (2005). The dinucleotide (CA) repeat polymorphism of estrogen receptor beta but not the dinucleotide (TA) repeat polymorphism of estrogen receptor alpha is associated with venous ulceration. J Steroid Biochem Mol Biol. 97(3), pp.266-270.
GS. Ashcroft, JJ. Ashworth (2003). Potential role of estrogens in wound healing. Am J Clin Dermatol. 4(11), pp.737-743.
GS. Ashcroft, SJ. Mills, JJ. Ashworth (2002). Ageing and wound healing. Biogerontology. 3(6), pp.337-345.
C. Parry, M. El Mohtadi, K. Whitehead, J. Ashworth (2018). Androgens inhibit phagocytosis by macrophages via the androgen receptor. Amsterdam, Netherlands, 2/9/2018.
M. El Mohtadi, K. Whitehead, J. Ashworth (2018). Estrogen stimulates phagocytosis by macrophages in both in vitro and ex vivo models of age-related impaired healing via the estrogen-receptor alpha. Amsterdam, Netherlands, 2/9/2018.
NR. Hall, M. Slevin, W. Gilmore, JJ. Ashworth (2017). The pentameric, but not the monomeric, isoform of C-reactive protein (CRP) enhances phagocytosis of methicillin-resistant Staphylococcus aureus (MRSA); potential implications for treatment strategies. Cold Spring Harbor Laboratory, New York, 12/9/2017.
M. El Mohtadi, KA. Whitehead, F. Abdulmannan, JJ. Ashworth (2017). Estrogen Enhances Host-Pathogen Interactions in an in vitro Model of Age-Related Impaired Healing. Cold Spring Harbor Laboratory, New York, 12/9/2017.
M. El Mohtadi, K. Whitehead, J. Ashworth (2017). Effect of sex steroid hormones (estrogen) on host-pathogen interactions in an in vitro model of age-related impaired healing,. Manchester Metropolitan University, Manchester, UK., 6/9/2017.
NR. Hall, M. Slevin, W. Gilmore, JJ. Ashworth (2015). The effect of C-reactive protein isoforms on nitric oxide production in U937 monocytes. Waterville Valley, NH, USA, 30/5/2015.
A. Yau, J. McLaughlin, RJ. Maughan, W. Gilmore, JJ. Ashworth, et al. (2014). The influence of glucagon-like-peptide-1 receptor single nucleotide polymorphisms on gastric emptying rate in Caucasian men. In: Proceedings of the Physiological Society. London, UK, 30/6/2014.
A. Yau, A. Moss, LJ. James, J. Hynes, JJ. Ashworth, et al. (2011). Serum angiotensin I-converting enzyme response to exercise; no differential effect of genotype. In: British Journal of Sports Medicine. pp.A4-A4.
A. Yau, A. Moss, LJ. James, JJ. Ashworth, GH. Evans (2011). The influence of bradykinin receptor B2 genetic variation on voluntary fluid intake and fluid balance. In: Proceedings of the Physiological Society. pp.PC201-PC201.
Dr Ashworth has reviewed for several journals including the Journal of the American Medical Association (JAMA) and the Nature Publishing Group (NPG).