Dr Debra Whitehead
Senior Lecturer
My profile
Biography
Prizes and awards
Poster Prize Nanomed 2015
Real-time observation of aortic vessel dilation through delivery of sodium nitroprusside via slow release mesoporous nanoparticles
Asima FAROOQ, Debra WHITEHEAD,Lubomira TOSHEVA, Peter KELLY, May AZZAWI.
Membership of professional associations
Member of the Royal Society of Chemistry (MRSC)
Fellow of the Higher Education Academy (FHEA)
Teaching
Postgraduate teaching
Supervision of PhD and MSc research students
Subject areas
Physical Chemistry
Supervision
PhD students
Helen Casey
Cai Astley (DOS: Dr May Azzawi)
If you are interested in working in our group, please contact me directly in the first instance by e-mail.
Funded opportunities will be posted here.
Ph.D. Positions: Self-funding candidates are invited to to discuss project proposals with me prior to application.
Post-doctoral Positions: If you are actively applying for your own funding (Research councils, charities, government agencies) to join our group then please contact me well in advance to receive substantial assistance with your application.
Research outputs
- Nanomedicine: Nanotoxicological influence of nanoparticles (Silica, mesoporous silica, gold, quantum dots) on cellular and vascular function. The aim is inform their safe application in diagnostics and therapeutics, particularly in the treatment of vascular disease.
- Nanosensors: nanoparticles for gas sensor development
- Nanoparticles for slow drug delivery
- Upconversion and doped nanoparticles for enhanced photocatalysis of water pollutants
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Journal articles
Astley, C., Houacine, C., Zaabalawi, A., Wilkinson, F., Lightfoot, A.P., Alexander, Y., Whitehead, D., Singh, K.K., Azzawi, M. (2021) 'Nanostructured lipid carriers deliver resveratrol, restoring attenuated dilation in small coronary arteries, via the AMPK pathway.' Biomedicines, 9(12)
Zaabalawi, A., Astley, C., Renshall, L., Beards, F., Lightfoot, A.P., Degens, H., Whitehead, D., Alexander, Y., Harris, L.K., Azzawi, M. (2019) 'Tetramethoxystilbene-Loaded Liposomes Restore Reactive-Oxygen-Species-Mediated Attenuation of Dilator Responses in Rat Aortic Vessels Ex vivo.' Molecules, 24(23)
Farooq, A., Shukur, A., Astley, C., Tosheva, L., Kelly, P., Whitehead, D., Azzawi, M. (2018) 'Titania coating of mesoporous silica nanoparticles for improved biocompatibility and drug release within blood vessels.' Acta Biomaterialia, 76pp. 208-216.
Azzawi, M., Mohamed, T., Matou-Nasri, S., Farooq, A., Whitehead, D. (2017) 'Polyvinylpyrrolidone-coated gold nanoparticles inhibit endothelial cell viability, proliferation, and ERK1/2 phosphorylation and reduce the magnitude of endothelial-independent dilator responses in isolated aortic vessels.' International Journal of Nanomedicine, 2017(12) pp. 8813-8830.
Frost, M., Dempsey, M.J., Whitehead, D.E. (2017) 'The Response of Citrate Functionalized Gold and Silver Nanoparticles to the Addition of Heavy Metal Ions.' Colloids and Surfaces A: Physicochemical and Engineering Aspects, 518pp. 15-24.
Shukur, A., Whitehead, D., Seifalian, A., Azzawi, M. (2016) 'The influence of silica nanoparticles on small mesenteric arterial function.' Nanomedicine, 11(16) pp. 2131-2146.
Whitehead, D.E., Farooq, A., Tosheva, L., Azzawi, M. (2016) 'Real-time observation of aortic vessel dilation through delivery of sodium nitroprusside via slow release mesoporous nanoparticles.' Journal of Colloid and Interface Science, 478pp. 127-135.
Frost, M.S., Dempsey, M.J., Whitehead, D.E. (2015) 'Highly sensitive SERS detection of Pb2+ ions in aqueous media using citrate functionalised gold nanoparticles.' Sensors and Actuators B: Chemical, 221
Farooq, A., Mohamed, T., Whitehead, D., Azzawi, M. (2014) 'Restored endothelial dependent vasodilation in aortic vessels after uptake of ceria coated silica nanoparticles, ex vivo.' Journal of Nanomedicine and Nanotechnology, 5
Ghosh, S., Dungdung, S.R., Choudhury, S.T., Chakraborty, S., Das, N. (2014) 'Mitochondria protection with ginkgolide B-loaded polymeric nanocapsules prevents diethylnitrosamine-induced hepatocarcinoma in rats.' Nanomedicine, 9(3) pp. 441-456.
Farooq, A., Whitehead, D., Azzawi, M. (2014) 'Attenuation of endothelial-dependent vasodilator responses, induced by dye-encapsulated silica nanoparticles, in aortic vessels..' Nanomedicine (Lond), 9(3) pp. 413-425.
Farooq, A., Al-Jowder, R., Narayanaswamy, R., Azzawi, M., Roche, P.J.R., Whitehead, D.E. (2013) 'Gas detection using quenching fluorescence of dye-immobilised silica nanoparticles.' Sensors and Actuators, B: Chemical, 183pp. 230-238.
Shukur, A., Rizvi, S.B., Whitehead, D., Seifalian, A., Azzawi, M. (2013) 'Altered sensitivity to nitric oxide donors, induced by intravascular infusion of quantum dots, in murine mesenteric arteries..' Nanomedicine, 9(4) pp. 532-539.
Akbar, N., Mohamed, T., Whitehead, D., Azzawi, M. (2011) 'Biocompatibility of amorphous silica nanoparticles: Size and charge effect on vascular function, in vitro.' BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 58(5) pp. 353-362.
Khunsin, W., Romanov, S.G., Bardosova, M., Whitehead, D., Pemble, M., Povey, I.M., Sotomayor Torres, C.M. (2008) 'Bleaching-induced evolution of directional emission from dye-loaded opals.' Journal of Optics A: Pure and Applied Optics, 10(11) pp. 115201-115201.
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Conference papers
Shukur, A., Whitehead, D., Seifalian, A.M., Alexander, Y., Wilkinson, F., Azzawi, M. (2015) 'INFUSED SILICA NANOPARTICLES COMPROMISE VASCULAR FUNCTION IN SMALL MESENTERIC ARTERIES.' In British-Cardiac-Society (BCS) Annual Conference on Hearts and Genes. 101. Manchester, ENGLAND, 8/6/2015 - 10/6/2015. BMJ PUBLISHING GROUP, pp. A98-A98.