ABOUT OUR RESEARCH
Cardiovascular diseases are a leading cause of morbidity and mortality worldwide.
These include diseases that are:
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a direct consequence of cardiac - such as cardiac rhythm disorders and cardiomyopathies
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vessel associated conditions - such as atherosclerosis, stroke and hypertension
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an indirect result of other influences - such as immobility, inactivity, obesity, inflammation, diabetes and renal disorders
Keeping our hearts and blood vessels healthy is pivotal to ensuring adequate tissue perfusion and organ function. Poor diameter regulation is an early sign of endothelial and vascular dysfunction and is associated with an increased risk of morbidity and mortality.
We use in-vitro, ex-vivo, and in-vivo approaches to investigate the mechanisms that underpin these conditions and explore therapeutic intervention strategies to alleviate their adverse consequences.